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1.
441 Accesses
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Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer
Sanjit K Roy, Rakesh K Srivastava, Sharmila Shankar Journal of Molecular Signaling 2010, 5:10 (19 July 2010)
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2.
331 Accesses
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NFAT5 in cellular adaptation to hypertonic stress – regulations and functional significance
Chris YK Cheung, Ben CB Ko Journal of Molecular Signaling 2013, 8:5 (23 April 2013)
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3.
317 Accesses
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The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition
Su-Ni Tang, Chandan Singh, Dara Nall, Daniel Meeker, Sharmila Shankar, Rakesh K Srivastava Journal of Molecular Signaling 2010, 5:14 (18 August 2010)
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4.
312 Accesses
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Assembly of Dishevelled 3-based supermolecular complexes via phosphorylation and Axin
Noriko Yokoyama, Nelli G Markova, Hsien-yu Wang, Craig C Malbon Journal of Molecular Signaling 2012, 7:8 (29 June 2012)
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5.
298 Accesses
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Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine
Vasileios A Stamelos, Charles W Redman, Alan Richardson Journal of Molecular Signaling 2012, 7:12 (16 August 2012)
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6.
296 Accesses
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Signaling in colon cancer stem cells
Sanchita Roy, Adhip PN Majumdar Journal of Molecular Signaling 2012, 7:11 (6 August 2012)
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7.
242 Accesses
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Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1
Yongxian Zhuang, W Keith Miskimins Journal of Molecular Signaling 2008, 3:18 (1 December 2008)
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8.
240 Accesses
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Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells
Jyoti Nautiyal, Shailender S Kanwar, Yingjie Yu, Adhip PN Majumdar Journal of Molecular Signaling 2011, 6:7 (20 July 2011)
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9.
240 Accesses
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Aggressive neuroblastomas have high p110alpha but low p110delta and p55alpha/p50alpha protein levels compared to low stage neuroblastomas
Susanne Fransson, Per Kogner, Tommy Martinsson, Katarina Ejeskär Journal of Molecular Signaling 2013, 8:4 (18 April 2013)
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10.
228 Accesses
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Caspase-3 mediated release of SAC domain containing fragment from Par-4 is necessary for the sphingosine-induced apoptosis in Jurkat cells
Faisal Thayyullathil, Siraj Pallichankandy, Anees Rahman, Jaleel Kizhakkayil, Shahanas Chathoth, Mahendra Patel, Sehamuddin Galadari Journal of Molecular Signaling 2013, 8:2 (27 February 2013)
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11.
226 Accesses
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AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia
Gilles M Leclerc, Guy J Leclerc, Guilian Fu, Julio C Barredo Journal of Molecular Signaling 2010, 5:15 (23 September 2010)
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12.
223 Accesses
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Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling
Benjamin J Ritchie, William C Smolski, Ellyn R Montgomery, Elizabeth S Fisher, Tina Y Choi, Calla M Olson, Lori A Foster, Thomas E Meigs Journal of Molecular Signaling 2013, 8:3 (25 March 2013)
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13.
218 Accesses
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Canonical Wnt signaling is involved in switching from cell proliferation to myogenic differentiation of mouse myoblast cells
Shingo Tanaka, Kumiko Terada, Tsutomu Nohno Journal of Molecular Signaling 2011, 6:12 (5 October 2011)
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14.
213 Accesses
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Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: molecular mechanisms of apoptosis, migration and angiogenesis
Sharmila Shankar, Qinghe Chen, Krishna Sarva, Imtiaz Siddiqui, Rakesh K Srivastava Journal of Molecular Signaling 2007, 2:10 (4 October 2007)
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15.
204 Accesses
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Gadd45 in stress signaling
Dan A Liebermann, Barbara Hoffman Journal of Molecular Signaling 2008, 3:15 (12 September 2008)
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16.
196 Accesses
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Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor
Sharmila Shankar, Qinghe Chen, Rakesh K Srivastava Journal of Molecular Signaling 2008, 3:7 (20 March 2008)
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17.
193 Accesses
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SFRP-4 abrogates Wnt-3a-induced β-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation
Thecla Constantinou, Fabrizio Baumann, Markus D Lacher, Susanne Saurer, Robert Friis, Arun Dharmarajan Journal of Molecular Signaling 2008, 3:10 (2 May 2008)
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18.
191 Accesses
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The adaptor protein p62/SQSTM1 in osteoclast signaling pathways
Stephen McManus, Sophie Roux Journal of Molecular Signaling 2012, 7:1 (4 January 2012)
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19.
184 Accesses
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Consequences of nongenomic actions of estradiol on pathogenic genital tract response
Paula Solar, Luis Velasquez Journal of Molecular Signaling 2013, 8:1 (26 January 2013)
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20.
184 Accesses
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Estradiol effects on the dopamine transporter – protein levels, subcellular location, and function
Cheryl S Watson, Rebecca A Alyea, Bridget E Hawkins, Mary L Thomas, Kathryn A Cunningham, Adrian A Jakubas Journal of Molecular Signaling 2006, 1:5 (5 December 2006)
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21.
177 Accesses
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Multiple paxillin binding sites regulate FAK function
Danielle M Scheswohl, Jessica R Harrell, Zenon Rajfur, Guanghua Gao, Sharon L Campbell, Michael D Schaller Journal of Molecular Signaling 2008, 3:1 (2 January 2008)
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22.
170 Accesses
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Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression
David C New, Yung H Wong Journal of Molecular Signaling 2007, 2:2 (26 February 2007)
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23.
158 Accesses
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EGFR/Met association regulates EGFR TKI resistance in breast cancer
Kelly L Mueller, Zeng-Quan Yang, Ramsi Haddad, Stephen P Ethier, Julie L Boerner Journal of Molecular Signaling 2010, 5:8 (12 July 2010)
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24.
154 Accesses
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AMPK exerts dual regulatory effects on the PI3K pathway
Rong Tao, Jun Gong, Xixi Luo, Mengwei Zang, Wen Guo, Rong Wen, Zhijun Luo Journal of Molecular Signaling 2010, 5:1 (18 February 2010)
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25.
148 Accesses
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NADPH oxidase mediates the oxygen-glucose deprivation/reperfusion-induced increase in the tyrosine phosphorylation of the N-methyl-D-aspartate receptor NR2A subunit in retinoic acid differentiated SH-SY5Y Cells
Phillip H Beske, Darrell A Jackson Journal of Molecular Signaling 2012, 7:15 (8 September 2012)
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