Open Access Short report

Activation of K-RAS by co-mutation of codons 19 and 20 is transforming

Adam Naguib1, Catherine H Wilson2, David J Adams 2 and Mark J Arends3*

1 Medical Research Council Dunn Human Nutrition Unit, Wellcome Trust/MRC Building, Cambridge, CB2 0XY, UK

2 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK

3 Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK, CB2 0QQ, UK

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Journal of Molecular Signaling 2011, 6:2 doi:10.1186/1750-2187-6-2

Published: 3 March 2011

Additional files

Additional file 1:

Experimental methods and statistical testing. Additional File 1 contains a detailed description of all experimental methods described in this manuscript. Furthermore, complete colony counts are available for all experiments in tabulated format.

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