Figure 1.

KDR, c-Src and SHP-1 co-precipitate and are part of one complex. (A) Serum starved HUVEC was treated with or without VEGF 10 ng/ml for 5 min and immunoprecipitated with antibody against KDR and immunoblotted with SHP-1 antibody. The first lane represents negative control (rabbit IgG). (B) Serum starved HUVEC was treated with or without VEGF 10 ng/ml for 5 min and immunoprecipitated with antibody against c-Src and immunoblotted with KDR and Src antibody.