Figure 6.

Effect of the Albuterol Pretreatment of Phenylephrine-Induced Contraction of the Rat Aorta. Panel A; Log-dose response curves of the ability of albuterol to relax the rat aorta. The aorta was contracted with KCl and the albuterol responses were assessed in control blood vessels and in those vessels desensitized by incubation with 1 uM albuterol for 12 hr. Data are the mean +/- the SEM of 10 (control) or 13 (desensitized) experiments. Panel B; Log-dose response curves for the ability of phenylephrine to induce contraction of the aorta following desensitization with albuterol. Data are the mean +/- the SEM of 6 independent experiments.