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Open AccessResearch article

Binding mode prediction of conformationally restricted anandamide analogs within the CB1 receptor

Lea W Padgett1,2 email, Allyn C Howlett1,3 email and Joong-Youn Shim1 email

1Neuroscience of Drug Abuse Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, NC 27707, USA

2Department of Chemistry and Physics, Armstrong Atlantic State University, Savannah, GA 31419, USA

3Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA

author email corresponding author email

Journal of Molecular Signaling 2008, 3:5doi:10.1186/1750-2187-3-5

Published: 26 February 2008

Additional files

Additional file 1:

Compound 1 poses within the CB1 receptor having optimal Affinity lowest energy values.

Format: WMV Size: 870KB Download file

Additional file 2:

Compound 2 poses within the CB1 receptor having optimal Affinity lowest energy values.

Format: WMV Size: 651KB Download file

Additional file 3:

Compound 6 poses within the CB1 receptor having optimal Affinity lowest energy values.

Format: WMV Size: 612KB Download file


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