Table 5

Prediction results of PLS regression using top vital signaling metrics.

G-CSF
 IL-1α
 IL-6
 IL-10
 MIP-1α
 RANTES
 TNFα
Numb. of metrics
 1
 1
 14
 34
 46
 1
 38
R2
 88.0 ± 0.27%
 51.4 ± 0.55%
 64.2 ± 2.41%
 56.6 ± 2.61%
 49.4 ± 2.42%
 75.0 ± 0.60%
 66.3 ± 1.84%

For each cytokine, a PLS regression model using from 1 to 46 of the most informative signaling metrics can achieve an average R2 greater than 85% of the maximum averaged R2. Values are means ± standard deviation. Numb. of metrics = Number of most informative metrics used in the regression.

Wu et al. Journal of Molecular Signaling 2008 3:11   doi:10.1186/1750-2187-3-11