Additional file 1.

Segment diagrams of the squared weighted VIP profile for G-CSF, IL-1α, IL-6, IL-10, MIP-1α and TNFα. For each cytokine, ten PLS models were generated through a 10-fold cross validation and then a weighted VIP score was computed as described in Materials and Methods to select important signaling metrics. A segment plot was produced for each protein, with the radial length of each segment indicating the magnitude of the squared weighted VIP score for individual metrics. VIP scores greater than 1 (dashed circle) are classified as significant metrics for each cytokine.

Format: PDF Size: 1.7MB Download file

This file can be viewed with: Adobe Acrobat Reader

Wu et al. Journal of Molecular Signaling 2008 3:11   doi:10.1186/1750-2187-3-11