Role of RGM coreceptors in bone morphogenetic protein signaling

doi:10.1186/1750-2187-2-4

Journal of Molecular Signaling

Volume 2

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Ding R
Wozney JM
Bain G

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Bain G
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Research article

Role of RGM coreceptors in bone morphogenetic protein signaling

Peter J Halbrooks¹ , Ru Ding² , John M Wozney² and Gerard Bain²

¹Quality Control Technical Services Laboratory, Genzyme Corporation, Framingham MA, 01701, USA

²Women's Health and Musculoskeletal Biology, Wyeth Discovery Research, Cambridge, MA, 02140, USA

author email corresponding author email

Journal of Molecular Signaling 2007, 2:4doi:10.1186/1750-2187-2-4


Published:	5 July 2007

Additional files

Additional file 1:

Biacore biosensor binding data. Sensorgrams from Biacore kinetic analysis of BMP2 and BMP12 binding to the RGM co-receptors. A concentration series of receptor is shown in color, with the kinetic fits (from BIAevaluation software) overlaid in black. Binding curves are shown for the interaction of RGMa/BMP2 (A), RGMa/BMP12 (B), RGMb/BMP2 (C), RGMb/BMP12 (D), RGMc/BMP2 (E), and RGMc/BMP12 (F).

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