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Journal of Molecular Signaling will encompass all the molecular aspects of cell signaling involving receptors, G-proteins, kinases, phosphatases, and transcription factors in regulating cell proliferation, differentiation, apoptosis, and oncogenesis in mammalian cells.
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Research article
SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB
signalling and reverses a Wnt-3a-imposed inhibition of in
vitro mammary differentiation Thecla Constantinou, Fabrizio Baumann, Markus D Lacher, Susanne Saurer, Robert Friis, Arun Dharmarajan Journal of Molecular Signaling 2008, 3 :10 (2 May 2008) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Enhanced catharanthine and vindoline production in suspension cultures of Catharanthus roseus by ultraviolet-B light Shilpa Ramani, Chelliah Jayabaskaran Journal of Molecular Signaling 2008, 3 :9 (25 April 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration* Resham Bhattacharya, Junhye Kwon, Enfeng Wang, Priyabrata Mukherjee, Debabrata Mukhopadhyay Journal of Molecular Signaling 2008, 3 :8 (31 March 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor Sharmila Shankar, Qinghe Chen, Rakesh K Srivastava Journal of Molecular Signaling 2008, 3 :7 (20 March 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
The α1D -adrenergic receptor is expressed intracellularly and coupled to increases in intracellular calcium and reactive oxygen species in human aortic smooth muscle cells Mary L García-Cazarín, Jennifer L Smith, Kyle A Olszewski, Dan F McCune, Linda A Simmerman, Robert W Hadley, Susan D Kraner, Michael T Piascik Journal of Molecular Signaling 2008, 3 :6 (27 February 2008) [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
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